DISEASES

Disease-gene associations mined from literature

Literature on RFTN2

RFTN2 [ENSP00000295049]

Raftlin-2; Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling; Belongs to the raftlin family.

Synonyms:  RFTN2,  RFTN2p,  hRFTN2,  C9J6C2,  H7BZ31 ...

Linkouts:  STRING  Pharos  UniProt