Literature on GRM1
GRM1 [ENSP00000282753]
Metabotropic glutamate receptor 1; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum . May function in the light response in the retina (By similarity).
Synonyms: GRM1, GRM1p, hGRM1, Q13255, Q13255p ...