DISEASES

Disease-gene associations mined from literature

Literature on TWF2

TWF2 [ENSP00000303908]

Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity); Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.

Synonyms:  TWF2,  TWF2p,  hTWF2,  D6RG15,  Q6IBS0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM