DISEASES

Disease-gene associations mined from literature

Literature on TRMT61A

TRMT61A [ENSP00000374399]

tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA . Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries ; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.

Synonyms:  TRMT61A,  TRMT61Ap,  hTRMT61A,  A0A024R6Q2,  C14orf172 ...

Linkouts:  STRING  Pharos  UniProt