DISEASES

Disease-gene associations mined from literature

Literature on ANKRD28

ANKRD28 [ENSP00000382379]

Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.

Synonyms:  ANKRD28,  ANKRD28p,  hANKRD28,  A0A024R2G8,  B4DIW9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM