Literature on EDEM3
EDEM3 [ENSP00000318147]
ER degradation-enhancing alpha-mannosidase-like protein 3; Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity (By similarity). ; Belongs to the glycosyl hydrolase 47 family.
Synonyms: EDEM3, EDEM3p, hEDEM3, A0A024R931, C1orf22 ...