Literature on LRRFIP1
LRRFIP1 [ENSP00000375857]
Leucine-rich repeat flightless-interacting protein 1; Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. ECO:0000269|PubMed:16199883, ECO:0000269|PubMed:19265123,
Synonyms: LRRFIP1, LRRFIP1p, hLRRFIP1, A0A0F7NGI8, C9JTC6 ...