DISEASES

Disease-gene associations mined from literature

Literature on PLA2G5

PLA2G5 [ENSP00000364249]

Calcium-dependent phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L- alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1- palmitoyl-2-arachidonyl phosphatidylethanolamine, or L-alpha-1- stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.

Synonyms:  PLA2G5,  PLA2G5p,  hPLA2G5,  P39877,  P39877p ...

Linkouts:  STRING  Pharos  UniProt  OMIM