Literature on RTN4RL2
RTN4RL2 [ENSP00000335397]
Reticulon-4 receptor-like 2; Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development . Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton .
Synonyms: RTN4RL2, RTN4RL2p, hRTN4RL2, G3V1D7, Q86UN3 ...