DISEASES

Disease-gene associations mined from literature

Literature on TXNDC17

TXNDC17 [ENSP00000250101]

Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide; Belongs to the thioredoxin family.

Synonyms:  TXNDC17,  TXNDC17p,  hTXNDC17,  A0A140VJY7,  I3L0K2 ...

Linkouts:  STRING  Pharos  UniProt