DISEASES

Disease-gene associations mined from literature

Literature on EFNA4

EFNA4 [ENSP00000414378]

Ephrin-A4; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

Synonyms:  EFNA4,  EFNA4p,  hEFNA4,  P52798,  P52798p ...

Linkouts:  STRING  Pharos  UniProt