DISEASES

Disease-gene associations mined from literature

Literature on SUSD4

SUSD4 [ENSP00000344219]

Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.

Synonyms:  SUSD4,  SUSD4p,  hSUSD4,  A0A140VK55,  B7Z369 ...

Linkouts:  STRING  Pharos  UniProt  OMIM