DISEASES

Disease-gene associations mined from literature

Literature on OSBPL6

OSBPL6 [ENSP00000376293]

Oxysterol-binding protein-related protein 6; Regulates cellular transport and efflux of cholesterol . Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol . ; Belongs to the OSBP family.

Synonyms:  OSBPL6,  OSBPL6p,  hOSBPL6,  Q9BZF3,  Q9BZF3p ...

Linkouts:  STRING  Pharos  UniProt  OMIM