DISEASES

Disease-gene associations mined from literature

Literature on RAP2B

RAP2B [ENSP00000319096]

Ras-related protein Rap-2b; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.

Synonyms:  RAP2B,  RAP2Bp,  hRAP2B,  P61225,  P61225p ...

Linkouts:  STRING  Pharos  UniProt  OMIM