DISEASES

Disease-gene associations mined from literature

Literature on PILRA

PILRA [ENSP00000198536]

Paired immunoglobulin-like type 2 receptor alpha; Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.

Synonyms:  PILRA,  C9JGG1,  C9JJ79,  Q9UKJ1,  C9JGG1p ...

Linkouts:  STRING  Pharos  UniProt  OMIM