DISEASES

Disease-gene associations mined from literature

Literature on TAF1B

TAF1B [ENSP00000263663]

TATA box-binding protein-associated factor RNA polymerase I subunit B; Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. ECO:0000269|PubMed:21921199, ECO:0000269|PubMed:7491500,; Belongs to the RRN7/TAF1B family.

Synonyms:  TAF1B,  TAF1Bp,  hTAF1B,  F8WDU0,  F8WE32 ...

Linkouts:  STRING  Pharos  UniProt  OMIM