DISEASES

Disease-gene associations mined from literature

Literature on KAT6A

KAT6A [ENSP00000265713]

Histone acetyltransferase KAT6A; Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:12771199, ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:17925393,

Synonyms:  KAT6A,  KAT6Ap,  hKAT6A,  A0A3B3IS53,  A0A3B3ISU5 ...

Linkouts:  STRING  Pharos  UniProt