DISEASES

Disease-gene associations mined from literature

Literature on TFDP1

TFDP1 [ENSP00000364519]

Transcription factor Dp-1; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication . The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters ; Belongs to the E2F/DP family.

Synonyms:  TFDP1,  TFDP1p,  hTFDP1,  A0A024RDY4,  F5H452 ...

Linkouts:  STRING  Pharos  UniProt  OMIM