DISEASES

Disease-gene associations mined from literature

Literature on CENPI

CENPI [ENSP00000362018]

Centromere protein I; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle- stimulating hormone; Belongs to the CENP-I/CTF3 family.

Synonyms:  CENPI,  A0A024RCG4,  FSHPRH1,  Q5JX01,  Q5JX02 ...

Linkouts:  STRING  Pharos  UniProt  OMIM