DISEASES

Disease-gene associations mined from literature

Literature on SLC25A28

SLC25A28 [ENSP00000359526]

Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.

Synonyms:  SLC25A28,  Q96A46,  X6RFA8,  Q96A46p,  hQ96A46 ...

Linkouts:  STRING  Pharos  UniProt  OMIM