DISEASES

Disease-gene associations mined from literature

Literature on ASB4

ASB4 [ENSP00000321388]

Ankyrin repeat and SOCS box protein 4; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism (By similarity); Belongs to the ankyrin SOCS box (ASB) family.

Synonyms:  ASB4,  ASB4p,  hASB4,  Q9Y574,  Q9Y574p ...

Linkouts:  STRING  Pharos  UniProt  OMIM