DISEASES

Disease-gene associations mined from literature

Literature on JSRP1

JSRP1 [ENSP00000300961]

Junctional sarcoplasmic reticulum protein 1; Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.

Synonyms:  JSRP1,  JSRP1p,  hJSRP1,  LOC105372240,  Q96MG2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM