DISEASES

Disease-gene associations mined from literature

Literature on EIF5A2

EIF5A2 [ENSP00000295822]

Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

Synonyms:  EIF5A2,  EIF5A2p,  hEIF5A2,  C9J4W5,  C9J7B5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM