DISEASES

Disease-gene associations mined from literature

Literature on AGPAT5

AGPAT5 [ENSP00000285518]

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor . Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl- CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA . Activity toward lysophosphatidylglycerol not detectable .

Synonyms:  AGPAT5,  AGPAT5p,  hAGPAT5,  A0A024R640,  E5RH21 ...

Linkouts:  STRING  Pharos  UniProt  OMIM