DISEASES

Disease-gene associations mined from literature

Literature on ASF1B

ASF1B [ENSP00000263382]

Histone chaperone ASF1B; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis. ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15664198,; Belongs to the ASF1 family.

Synonyms:  ASF1B,  ASF1Bp,  hASF1B,  A0A024R7G4,  K7EIL9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM