DISEASES

Disease-gene associations mined from literature

Literature on NME3

NME3 [ENSP00000219302]

Nucleoside diphosphate kinase 3; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis; Belongs to the NDK family.

Synonyms:  NME3,  NME3p,  hNME3,  H3BMQ7,  H3BPD9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM