Literature on USP18
USP18 [ENSP00000215794]
Ubl carboxyl-terminal hydrolase 18; Involved in the regulation of inflammatory response to interferon type 1 . Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. ; Belongs to the peptidase C19 family.
Synonyms: USP18, USP18p, hUSP18, Q9UMW8, Q9UMW8p ...