DISEASES

Disease-gene associations mined from literature

Literature on RNF19B

RNF19B [ENSP00000362555]

E3 ubiquitin-protein ligase RNF19B; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1 . Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells . Protects against staurosporin-induced cell death .

Synonyms:  RNF19B,  RNF19Bp,  hRNF19B,  Q6ZMZ0,  Q6ZMZ0p ...

Linkouts:  STRING  Pharos  UniProt  OMIM