DISEASES

Disease-gene associations mined from literature

Literature on RAB8B

RAB8B [ENSP00000312734]

Ras-related protein Rab-8B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells (By similarity).

Synonyms:  RAB8B,  RAB8Bp,  hRAB8B,  H0YL94,  H0YLJ8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM