DISEASES

Disease-gene associations mined from literature

Literature on PATL1

PATL1 [ENSP00000300146]

Protein PAT1 homolog 1; RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV). ECO:0000269|PubMed:19628699, ECO:0000269|PubMed:20543818,; Belongs to the PAT1 family.

Synonyms:  PATL1,  PATL1p,  hPATL1,  Q86TB9,  Q86TB9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM