DISEASES

Disease-gene associations mined from literature

Literature on ZFYVE21

ZFYVE21 [ENSP00000216602]

Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression.

Synonyms:  ZFYVE21,  ZFYVE21p,  hZFYVE21,  G3V2M2,  G3V5D6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM