DISEASES

Disease-gene associations mined from literature

Literature on HCAR3

HCAR3 [ENSP00000436714]

Hydroxycarboxylic acid receptor 3; Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta- oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Synonyms:  HCAR3,  HCAR3p,  hHCAR3,  P49019,  P49019p ...

Linkouts:  STRING  Pharos  UniProt