DISEASES

Disease-gene associations mined from literature

Literature on NRG4

NRG4 [ENSP00000378367]

Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).

Synonyms:  NRG4,  NRG4p,  hNRG4,  E9PJI7,  H3BP63 ...

Linkouts:  STRING  Pharos  UniProt  OMIM