DISEASES

Disease-gene associations mined from literature

Literature on SEPTIN6

SEPTIN6 [ENSP00000341524]

Septin-6; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation . ; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

Synonyms:  SEPTIN6,  SEPTIN6p,  hSEPTIN6,  B1AMS2,  Q14141 ...

Linkouts:  STRING  Pharos  UniProt  OMIM