DISEASES

Disease-gene associations mined from literature

Literature on FGD3

FGD3 [ENSP00000336914]

FYVE, RhoGEF and PH domain-containing protein 3; Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).

Synonyms:  FGD3,  FGD3p,  hFGD3,  A0A024R252,  Q5JSP0 ...

Linkouts:  STRING  Pharos  UniProt