Literature on DBF4B
DBF4B [ENSP00000323663]
Protein DBF4 homolog B; Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.
Synonyms: DBF4B, DBF4Bp, hDBF4B, B4E099, Q8NFT6 ...