DISEASES

Disease-gene associations mined from literature

Literature on PRDX2

PRDX2 [ENSP00000301522]

Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).

Synonyms:  PRDX2,  PRDX2p,  hPRDX2,  A6NIW5,  HEL-S-2a ...

Linkouts:  STRING  Pharos  UniProt  OMIM