DISEASES

Disease-gene associations mined from literature

Literature on CDK2AP2

CDK2AP2 [ENSP00000301488]

Cyclin-dependent kinase 2-associated protein 2; Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A .

Synonyms:  CDK2AP2,  CDK2AP2p,  hCDK2AP2,  DOC-1R,  E9PKR4 ...

Linkouts:  STRING  Pharos  UniProt