DISEASES

Disease-gene associations mined from literature

Literature on NEMF

NEMF [ENSP00000298310]

Nuclear export mediator factor NEMF; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex . May indirectly play a role in nuclear export .

Synonyms:  NEMF,  G3V4D9,  G3V547,  G3V5V3,  O60524 ...

Linkouts:  STRING  Pharos  UniProt