DISEASES

Disease-gene associations mined from literature

Literature on PTPN23

PTPN23 [ENSP00000265562]

Tyrosine-protein phosphatase non-receptor type 23; Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes . May act as a negative regulator of Ras-mediated mitogenic activity . Plays a role in ciliogenesis .

Synonyms:  PTPN23,  PTPN23p,  hPTPN23,  C9JD91,  Q9H3S7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM