DISEASES

Disease-gene associations mined from literature

Literature on OTUB2

OTUB2 [ENSP00000203664]

Ubiquitin thioesterase OTUB2; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains; Belongs to the peptidase C65 family.

Synonyms:  OTUB2,  OTUB2p,  hOTUB2,  Q96DC9,  Q96DC9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM