DISEASES

Disease-gene associations mined from literature

Literature on CEMIP2

CEMIP2 [ENSP00000366243]

Cell surface hyaluronidase; Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate- size hyaluronan of approximately 5 kDa fragments . Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate .

Synonyms:  CEMIP2,  CEMIP2p,  hCEMIP2,  A0A024R229,  B4E1B9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM