DISEASES

Disease-gene associations mined from literature

Literature on ACAP1

ACAP1 [ENSP00000158762]

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. ECO:0000269|PubMed:17398097, ECO:0000269|PubMed:17664335,

Synonyms:  ACAP1,  ACAP1p,  hACAP1,  I3L0K9,  I3L268 ...

Linkouts:  STRING  Pharos  UniProt  OMIM