DISEASES

Disease-gene associations mined from literature

Literature on OSBPL1A

OSBPL1A [ENSP00000320291]

Oxysterol-binding protein-related protein 1; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A . Binds 25-hydroxycholesterol and cholesterol ; Belongs to the OSBP family.

Synonyms:  OSBPL1A,  OSBPL1Ap,  hOSBPL1A,  A0A1W2PRU5,  B0YJ56 ...

Linkouts:  STRING  Pharos  UniProt  OMIM