Literature on SLF1
SLF1 [ENSP00000265140]
SMC5-SMC6 complex localization factor protein 1; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance . The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks . Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions .
Synonyms: SLF1, SLF1p, hSLF1, D6RED9, H0YBU1 ...