DISEASES

Disease-gene associations mined from literature

Literature on RIPOR1

RIPOR1 [ENSP00000400099]

Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration . Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation . Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation . ; Belongs to the RIPOR family.

Synonyms:  RIPOR1,  RIPOR1p,  hRIPOR1,  A0A0A0MTL6,  A0A0G2JLA4 ...

Linkouts:  STRING  Pharos  UniProt