DISEASES

Disease-gene associations mined from literature

Literature on TMBIM6

TMBIM6 [ENSP00000389277]

Bax inhibitor 1; Suppressor of apoptosis . Modulates unfolded protein response signaling . Modulates ER calcium homeostasis by acting as a calcium-leak channel . Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).

Synonyms:  TMBIM6,  TMBIM6p,  hTMBIM6,  A0A024R0Z5,  A0A0G2JKZ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM