Literature on ZMYND11
ZMYND11 [ENSP00000371003]
Zinc finger MYND domain-containing protein 11; Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA . Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
Synonyms: ZMYND11, ZMYND11p, hZMYND11, A0A0A0MRY2, B0QZE2 ...