DISEASES

Disease-gene associations mined from literature

Literature on SGIP1

SGIP1 [ENSP00000360076]

SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.

Synonyms:  SGIP1,  SGIP1p,  hSGIP1,  F6R8P8,  Q6ZV33 ...

Linkouts:  STRING  Pharos  UniProt  OMIM