DISEASES

Disease-gene associations mined from literature

Literature on SHANK2

SHANK2 [ENSP00000345193]

SH3 and multiple ankyrin repeat domains protein 2; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Synonyms:  SHANK2,  SHANK2p,  hSHANK2,  A0A087X158,  A0A0A0MSQ6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM